Antibiotic, Bactericidal, Aminoglycoside Antibiotic, Ototoxic drug, Nephrotoxic drug
Amifuse E, Amiglyde-V®, Amiject D, Amikacin C Injection, Amikacin E, Amikacin K-9, Amikin®, Amimax™ C, Amimax™ E, Caniglide™, Equi-Phar EquiGlide™
Aminoglycoside bactericidal antibiotic
- Contraindicated in patients with known sensitivity to this type of drug.
- Use with extreme caution with pre existing renal disease and with close monitoring and dose interval adjustment.
- Use with caution in neonates and geriatric patients, fever, sepsis and dehydration.
- Use with caution in patients with neuromuscular disease due to the neuromuscular blocking activity.
- Contraindicated in pregnancy.
- Do not use in animals intended for human consumption.
- Don’t breed mare for at least 8 hours after intrauterine infusion.
- Can cause irreversible ototoxicity – use with caution in working dogs, i.e. seeing eye dogs.
- Cats may be more sensitive to toxic effects.
- Contraindicated in rabbits as they adversely affect GI flora.
- Nephrotoxic, ototoxic auditory or vestibular.
- Can also cause neuromuscular blockade and respiratory paralysis, facial edema, pain and inflammation at injection site, peripheral neuropathy and hypersensitivity reactions.
- Rarely GI, hematologic and hepatic.
- Neuromuscular blockade effects may be potentiated.
- May cause additive nephrotoxicity-only documented with cephalothin.
- May increase toxicity.
- May increase risk of nephrotoxicity.
- May be potentiated.
- May increase risk of ototoxicity.
- May cause additive nephrotoxicity.
- Nephrotoxicity is enhanced with furosemide.