Diuretic, Glaucoma treatment, Osmotic diuretic
Brand Names
Osmoglyn®
Drug Information
Pharmacology
Glycerol.
Contraindications
General
- Contraindicated in patients with known sensitivity to this type of drug.
- Contraindicated in anuria, severe dehydration, severe heart failure and pulmonary edema.
- Give with caution in patients with hypovolemia, heart disease or diabetes.
- Use only when benefit outweighs the risk during pregnancy as safety has not been established.
Adverse Effects
General
- Vomiting after dosing is most common.
- Humans have reported headache, nausea, thirst and diarrhea.
Interactions
General Interactions
- Topical miotic agents may prolong the IOP lowering effects of glycerin.
Category Interactions
Carbonic Anhydrase Inhibitor
- Carbonic anhydrase inhibitors may prolong the IOP lowering effects of glycerin.
Available Forms
Human
- Oral liquid 50% (0.6 gm/mL) in 220 mL btls; Osmoglyn®. Also available in topical ophthalmic preps and suppository or liquid form for laxative use.
Veterinary – General
- None
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