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Maxitrol (NPB + Dex)

Antiinflammatory, Antibiotic, Bactericidal, Topical ophthalmic, Eye drop, Topical corticosteroid, Topical antibiotic / corticosteroid

Brand Names

Corticosporin®, Maxitrol®, Neo-Predef® ointment, NeoDecadron®, Neopredef ointment, Optisone®

Drug Information

Pharmacology

Broad spectrum bactericidal topical antibiotic corticosteroid combination.

Contraindications

Cat
  • Due to the risk of severe anaphylaxis and death, some feel triple antibiotic combination therapy is contraindicated in cats.

Adverse Effects

General
  • Hypersensitivity reactions are possible and thought to be related to neomycin allergy.
Cat
  • There are sporadic reports of anaphylaxis and death in cats associated with the use of triple antibiotic ophthalmic products that contain neomycin.

Comments

Antibiotic preparation with hydrocortisone is a relatively weak anti-inflammatory product.
Antibiotic preparation with dexamethasone is a more potent anti-inflammatory product and
is used in more severe cases of inflammation.

Available Forms

Human
  • Ointment – Neomycin/polymixin B with Dexamethasone; Maxitrol ®. Neomycin with Dexamethasone; NeoDecadron ® Solutions – Neomycin/polymixin B with Dexamethasone; Maxitrol ®. Neomycin with Dexamethasone; NeoDecadron ® Neosporin/polymixin B and hydrocortisone; Corticosporin ®
Veterinary – General
  • Neomycin / PrednisoLONE in 3.5 gram tubes; Optisone ®. Approved for dogs and cats. Neomycin / Isoflupredone in 3.5 and 5 gram tubes; Neo-Predef ® Ointment. Approved for horses, dogs, cats and cattle.

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