Blood pressure treatment, Shock Treatment, Sympathomimetic, Alpha agonist
Alpha adrenergic sympathomimetic amine-causes peripheral vasoconstriction.
- Contraindicated in severe hypertension, ventricular tachycardia and in patients with known sensitivity to this type of drug.
- Use with extreme caution in geriatrics, hyperthyroidism, bradycardia, partial heart block or heat disease.
- Not to be used as a substitute for adequate volume replacement in patients with shock.
- Reflex bradycardia, CNS excitement, restlessness and headache are possible.
- Blood pressure needs to be monitored for hypertension.
- Extravasation may cause severe tissue reactions and necrosis.
Alpha adrenergic blocker
- Higher doses may be required if alpha blockers is used.
MAOI – Monoamine Oxidase Inhibitor
- MAO inhibitors are contraindicated as pronounced pressor effects are likely. Do not give within 2 weeks of each other.
- Higher doses may be required if phenothiazines are used.
- Atropine will block the bradycardia effects.
- Pressor effect may be enhanced with oxytocin.
- Injection 10 mg/mL; Neo-Synephrine®, generic. Also available in ophthalmic, intranasal forms with decongestants and antihistamines.
Veterinary – General